Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
| Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
| Upregulated in class | absentNotch |
| GeneSet | BIOCARTA_ACTIONS OF NITRIC OXIDE IN THE HEART |
| Enrichment Score (ES) | -0.70786023 |
| Normalized Enrichment Score (NES) | -1.5169696 |
| Nominal p-value | 0.012295082 |
| FDR q-value | 0.30584517 |
| FWER p-Value | 0.99 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | TNNI1 | 3710040 | 2287 | 0.203 | -0.0816 | No | ||
| 2 | PDE2A | 6100504 | 2593 | 0.163 | -0.0648 | No | ||
| 3 | PDE3B | 2030563 | 3125 | 0.102 | -0.0726 | No | ||
| 4 | PRKG2 | 1110465 | 3469 | 0.080 | -0.0748 | No | ||
| 5 | NOS3 | 630152 670465 | 4516 | 0.042 | -0.1226 | No | ||
| 6 | HSP90AA1 | 4560041 5220133 2120722 | 5268 | 0.027 | -0.1575 | No | ||
| 7 | FLT1 | 3830167 4920438 | 5302 | 0.027 | -0.1538 | No | ||
| 8 | BDKRB2 | 4780706 | 5415 | 0.025 | -0.1547 | No | ||
| 9 | GUCY1B3 | 2970020 | 5648 | 0.023 | -0.1626 | No | ||
| 10 | GUCY1B2 | 2120128 | 6079 | 0.018 | -0.1820 | No | ||
| 11 | KNG1 | 6400576 6770347 | 6117 | 0.018 | -0.1804 | No | ||
| 12 | GNAQ | 430670 4210131 5900736 | 7211 | 0.011 | -0.2370 | No | ||
| 13 | GUCY1A2 | 1660441 | 8076 | 0.007 | -0.2821 | No | ||
| 14 | CAV1 | 870025 | 8419 | 0.006 | -0.2992 | No | ||
| 15 | CHRM1 | 4280619 | 8458 | 0.006 | -0.3000 | No | ||
| 16 | PIK3R1 | 4730671 | 8693 | 0.005 | -0.3115 | No | ||
| 17 | CAMK2B | 2760041 | 8972 | 0.004 | -0.3256 | No | ||
| 18 | KDR | 3610286 | 9382 | 0.003 | -0.3470 | No | ||
| 19 | RYR2 | 2760671 | 10169 | 0.001 | -0.3890 | No | ||
| 20 | PDE3A | 380068 | 10540 | 0.000 | -0.4089 | No | ||
| 21 | AKT1 | 5290746 | 11232 | -0.001 | -0.4458 | No | ||
| 22 | CHRNA1 | 1170025 3610364 5220292 | 11547 | -0.002 | -0.4622 | No | ||
| 23 | GUCY2F | 2450309 | 12181 | -0.004 | -0.4954 | No | ||
| 24 | PRKAR1B | 6130411 | 12265 | -0.005 | -0.4989 | No | ||
| 25 | PIK3CA | 6220129 | 12641 | -0.006 | -0.5179 | No | ||
| 26 | GNGT1 | 5220156 | 12750 | -0.006 | -0.5224 | No | ||
| 27 | FLT4 | 1240292 6350707 | 13500 | -0.011 | -0.5605 | No | ||
| 28 | GUCY1A3 | 110253 2640735 4070037 | 13613 | -0.012 | -0.5642 | No | ||
| 29 | PRKG1 | 4120671 | 13666 | -0.012 | -0.5645 | No | ||
| 30 | PLCG1 | 6020369 | 13898 | -0.015 | -0.5739 | No | ||
| 31 | SLC7A1 | 2450193 2710241 | 14283 | -0.020 | -0.5904 | No | ||
| 32 | GUCY2C | 110411 6110156 | 14778 | -0.034 | -0.6100 | No | ||
| 33 | PRKAR2B | 3130593 5220577 | 15697 | -0.087 | -0.6417 | Yes | ||
| 34 | PRKAR2A | 2340136 | 15854 | -0.100 | -0.6297 | Yes | ||
| 35 | GNB1 | 2120397 | 17307 | -0.386 | -0.6291 | Yes | ||
| 36 | PDPK1 | 6650168 | 17599 | -0.496 | -0.5433 | Yes | ||
| 37 | VEGFA | 2940338 | 17821 | -0.587 | -0.4352 | Yes | ||
| 38 | PRKAR1A | 3450369 | 18326 | -0.974 | -0.2632 | Yes | ||
| 39 | PRKACB | 4210170 | 18485 | -1.364 | 0.0071 | Yes |
